Movie - The Crazies (2010)

A husband and wife in a small Midwestern town find themselves battling for survival as their friends and family descend into madness in The Crazies. A mysterious toxin in the water supply turns everyone exposed to it into mindless killers and the authorities leave the uninfected to their certain doom in this terrifying reinvention of the George Romero horror classic. Directed by Breck Eisner (Sahara), The Crazies is written by Ray Wright (Pulse, Case 39) and Scott Kosar (The Amityville Horror, The Texas Chainsaw Massacre). The American Dream goes horribly wrong when the residents of this picture-perfect town begin to succumb to an uncontrollable urge for violence and the horrific bloodshed escalates into anarchy. In an attempt to contain the epidemic, the military uses deadly force to close off access into or out of town, abandoning the few healthy citizens to the growing mayhem as depraved killers lurk in the shadows. Sheriff David Dutton (Timothy Olyphant); his pregnant wife, Judy (Radha Mitchell); Becca (Danielle Panabaker), an assistant at the medical center; and Russell (Joe Anderson), Dutton’s deputy and right-hand man, find themselves trapped in a once idyllic town they can no longer recognize. Unable to trust former neighbors and friends, deserted by the authorities and terrified of contracting the illness themselves, they are forced to band together in a nightmarish struggle for survival. (Source)

Anarchy takes over a quiet small town when a mysterious virus infection turns its inhabitants into depraved, blood-thirsty killers. (Source)

Sahara director Breck Eisner teams with screenwriters Ray Wright (Pulse) and Scott Kosar (The Texas Chainsaw Massacre) to give George A. Romero's underrated 1973 shocker a shiny new makeover in this update starring Timothy Olyphant and Radha Mitchell. Perform a Google search on "small-town America," and eventually you'll stumble across Ogden Marsh, a picturesque hamlet situated a safe distance from the nearest big city, and full of friendly faces. The citizens of Ogden Marsh are happy, albeit unremarkable people, but they're about to discover just how fragile their warm slice of the American Dream really is. When a mysterious toxin transforms the locals into murderous maniacs, it's up to Sheriff David Dutton (Olyphant) to find out why a man who was once an upstanding citizen would attempt to massacre the local youth baseball team, and a caring father would burn his beloved family alive. Within days the town has descended into total chaos, and the government has ordered it quarantined. Anyone who attempts to escape will be shot on sight, whether they're infected or not. Realizing that their only hope for survival is to fight through the madness that has consumed their once-quiet town, Sheriff Dutton, his pregnant wife, Judy (Mitchell), his deputy Russell (Joe Anderson), and frightened medical center assistant Becca (Danielle Panabaker) wage an epic struggle to discover the source of this malevolent scourge while fending off their infected friends and neighbors. - Jason Buchanan, All Movie Guide (Source)